In Assassin's Creed II, for the "I am Become Death, the Destroyer of Worlds" truth puzzle, turn the code wheel so the 9 matches with the solid triangle.
Match the 5 with a circle with two squares, the 2 with a circle, and the 9 with the sold triangle. Then on the next screen, press the red button.
Finally highlight the hidden group of numbers on the lower left corner of the paper and ID it.
There are 20 Glyphs, and thus 20 Glyph puzzles. Completing the Glyph puzzles is the key to unlocking “The Truth” video.
The puzzles aren't tied to particular Glyphs -- they follow a set sequence, regardless of the order you discover the Glyphs.
Unlock all 20 pieces of Subject 16's video to earn the “Vitruvian Man” Xbox 360 achievement or PlayStation 3 trophy. Find a guide to solving each Glyph puzzle at Super Cheats.
You can also view Glyph Solutions at IGN.com.