Yes, but not all Target stores sell stamps. It is recommended to contact your local Target store or visit the Guest Service desk to ask.
The USPS (United States Postal Service) consignment program provides alternatives for customers who would like to purchase stamps but do not want to go to a post office.
There are over 48,000 locations across the country as of 2010 that sell stamps. Retailers participating in the consignment program do not get compensation and may not sell stamps for more than the current postal prices.
View stamps pricing information at USPS - Postage Rates & Prices page.
Order stamps online through The USPS Postal Store.
Tip! Check out this USPS Customer's Guide to Mailing to help you choose the services that are best for you.