There are fourteen Motor Vehicle Department (MVD) offices in the Phoenix Metro area, and none of the offices have hours on Saturday and Sunday. You may be able to save yourself a trip into an office by checking out their online services, where you can renew registrations, order renewal or replacement licenses and registrations, change your address and do other MVD tasks.
Arizona also has authorized third party offices that are operated by private individuals and businesses. They are able to perform services such as titles, registrations, inspections and driver services. Many of these offices will have weekend hours.
The Arizona Department of Transportation has a Road Conditions section, where you can check up-to-date road restrictions and closures. To see road closures in Arizona, click here.