No. “Red Devil Lye” is 100% lye which means it's 100% made of caustic soda (Sodium Hydroxide, NaOH), Drain Out Crystal uses Caustic Soda with Aluminum Chips. According to sources, “Drain Out Crystal” has small white crystals and then some tiny black specks about the size of a grain of salt while “Red Devil Lye” is made up of all white crystals.
They are both drain cleaners, but Red Devil Lye was discontinued because of storage and safety issues. It was used by many home soap makers as an ingredient for lye-based soap. And since it is made of pure sodium hydroxide and was readily available, this product was frequently used by illegal "meth (methamphetamines)" labs to produce illicit drugs, as sodium hydroxide is a key ingredient in the manufacture of methamphetamines.
According to SI Restoration, drains and outflows should be inspected regularly as blocked or clogged drains are one of the key reasons why areas flood in situations involving frozen pipes. Find out more at EIN News.