Not Medical Advice: Yes, dissolving Vicodin, or any medication will make it work faster. This is because our bodies absorb the medication faster when dissolved (it takes around 30 minutes for our gastrointestinal tracts to digests most whole pills).
Pills must be digested in our stomachs, go through our intestinal tracts (where absorption occurs), and then off to the liver for more filtering. Dissolving a medication bypasses those processes, and delivers it straight to the blood stream. Keep in mind, all medication should only be taken as prescribed by your doctor!
Vicodin (hydrocodone) is a narcotic pain reliever, containing hydrocodone and acetaminophen. The prescription medication works in the brain changing how your body feels and responds to pain. Vicodin is highly addictive, and may cause withdrawal symptoms, especially if it has been used regularly for long periods of time or in high doses. Side effects of the drug are nausea, vomiting, constipation, dizziness, or drowsiness.
There's a new breakthrough in pain management called spinal cord stimulation. The system is a device called a generator that is similar in size and function to a cardiac pacemaker with leads (thin wires) that send pulses to nerves along the spinal cord, thus relieving pain. This new breakthrough is said to be a good alternative to narcotic pain medications.